Sildenafil Mesylate

[ Appearance ] White crystalline powder

[ Specification ]   1kg/20kg/50kg are available

[ Dry loss weight ]  0.5%max

[ Cauterant residue ]  <0.05%

[ Heavy metal ]  10ppm max

[ Functions and use ]  It is medicine treatment raw material, indicated for the treatment of erectile dysfunction.

[ Property ]  It is the ramification of Sildenafil Citrate, it is white to off-white crystalline powder, odorlessbitter taste, soluble in water and ethanol.

[ Mechanism ] Sildenafil Mesylate, same as Sildenafil is an inhibitor of type 5 -cGMP phosphodiesterase relaxing and smoothing muscle cells of the corpus cavernosum which leads to penile erection. This relaxation may be mediated by nitric oxide via cyclic guanosine monophosphate (cGMP).

[ Efficacy ]  52% will takes effect 30 minutes after taking, 82% takes effect 1 hour after taking for Sildenafil Mesylate. It has a terminal half-life of 5-12 hours. Its suggested dosage should be 100-150mg, and 120mg is suggested for the orient.

[ Storage ]  sealed in room temperature .